Browsing by Author "Karakus, Gulderen"
Now showing items 1-12 of 12
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Concentration modulated skin marker for radiotherapy treatment planning process
Ozguven, Yildiray; Yucel, Birsen; Ozyurek, Betul; Karakus, Gulderen; Ozguven, Yucel (ELSEVIER SCI LTD, 2013)Background and purpose: For conformal radiotherapy, it is feasible to achieve high accuracy in contouring the outline of the target volume in treatment planning process. In contouring process, target volume is occasionally ... -
Cytotoxic effect of acriflavine against clinical isolates of Acanthamoeba spp
Polat, Zubeyda Akin; Karakus, Gulderen (SPRINGER, 2013)Acanthamoeba keratitis (AK) is a potentially devastating and sight-threatening infection of the cornea caused by the ubiquitous free-living amoebae, Acanthamoeba species. Its eradication is difficult because the amoebas ... -
Cytotoxicity of three maleic anhydride copolymers and common solvents used for polymer solvation
Karakus, Gulderen; Zengin, Haci Bayram; Polat, Zubeyde Akin; Yenidunya, Ali Fazil; Aydin, Semiha (SPRINGER, 2013)Three maleic anhydride copolymers were synthesized by free-radical copolymerization. The synthesized products were named as follows: maleic anhydride-styrene (MAST); maleic anhydride-vinyl acetate (MAVA), and maleic ... -
Derivatization of Some Maleic Anhydride Containing Copolymers with Amine Functionalized Pharmaceutical Active Substances, Structural Characterizations and Biological Activities
Karakus, Gulderen (MARMARA UNIV, FAC PHARMACY, 2015)Poly(maleic anhydride-co-styrene) (MAST), poly(maleic anhydride-co-vinyl acetate) (MAVA), poly(maleic anhydride-co-methyl methacrylate) (MAMMA), poly(maleic anhydride-co-allyl phenyl ether) (MAAFE) and poly(maleic ... -
The effects of therapeutic x-ray doses on mechanical, chemical and physical properties of poly methyl methacrylate
Dogan, Derya Ozdemir; Ozguven, Yildiray; Karakus, Gulderen; Sahin, Onur; Polat, Nilufer Tulin; Yucel, Birsen; Dogan, Mansur (INFORMA HEALTHCARE, 2013)Aim. The aim of this study was to investigate the effect of radiation doses very close to the human dose for oral cancers on mechanical, chemical and physical properties for poly methyl-methacrylate (PMMA). Methods. PMMA ... -
Modification of Maleic Anhydride-Styrene Copolymer with Noradrenaline by Chemical and Enzymatic Methods
Karakus, Gulderen; Yenidunya, Ali Fazil; Zengin, Haci Bayram; Polat, Zubeyde Akin (WILEY-BLACKWELL, 2011)Maleic anhydride copolymer was modified with another biologically active agent, noradrenaline (NA), using both chemical and enzymatic methods. The modification and synthesized products were named as follows: chemical ... -
Sequential determination of serum viral titers, virus-specific IgG antibodies, and TNF-alpha, IL-6, IL-10, and IFN-gamma levels in patients with Crimean-Congo hemorrhagic fever
Kaya, Safak; Elaldi, Nazif; Kubar, Ayhan; Gursoy, Nevcihan; Yilmaz, Meral; Karakus, Gulderen; Gunes, Turabi; Polat, Zubeyde; Gozel, Mustafa Gokhan; Engin, Aynur; Dokmetas, Ilyas; Bakir, Mehmet; Yilmaz, Neziha; Sencan, Mehmet (BIOMED CENTRAL LTD, 2014)Background: Although there have been a number of studies on the pathogenesis of Crimean-Congo hemorrhagic fever (CCHF) recently, knowledge on this topic is still insufficient. This study aims to reveal the kinetics of serum ... -
Synthesis, characterization and antiproliferative activities of novel modified poly (maleic anhydride-co-vinyl acetate)/cytosine beta-D-arabinofuranoside hydrochloride conjugate
Karakus, Gulderen; Yaglioglu, Ayse Sahin; Zengin, Haci Bayram; Karakus, Nihat (MARMARA UNIV, FAC PHARMACY, 2015)Poly (maleic anhydride-co-vinyl acetate) (MAVA) copolymer was synthesized by free-radical-polymerization reaction in methyl ethyl ketone (MEK) at 80 degrees C using benzoyl-peroxide (BPO) as the radical-initiator. MAVA was ... -
Synthesis, characterization and cytotoxicity of novel modified poly[(maleic anhydride)-co-(vinyl acetate)]/noradrenaline conjugate
Karakus, Gulderen; Polat, Zubeyde Akin; Yenidunya, Ali Fazil; Zengin, Haci Bayram; Karakus, Can Bulent (WILEY-BLACKWELL, 2013)Poly[(maleic anhydride)-co-(vinyl acetate)] (MAVA) copolymer was synthesized by free radical polymerization reaction, in methyl ethyl ketone at 80 degrees C, using benzoyl peroxide as the initiator. The copolymer was then ... -
Synthesis, characterization and in vitro antibacterial assessments of a novel modified poly[maleic anhydride-alt-acrylic acid]/acriflavine conjugate
Can, Hatice Kaplan; Karakus, Gulderen; Tuzcu, Nevin (SPRINGER, 2014)Water-soluble maleic anhydride-containing poly[maleic anhydride-alt-acrylic acid] (poly(MA-alt-AA) or MAAA) copolymer was synthesized by freer-adical chain polymerization reaction, in 1,4-dioxane in the presence of benzoyl ... -
Synthesis, characterization, and assessment of cytotoxic, antiproliferative, and antiangiogenic effects of a novel procainamide hydrochloride-poly(maleic anhydride-co-styrene) conjugate
Karakus, Gulderen; Polat, Zubeyde Akin; Yaglioglu, Ayse Sahin; Karahan, Mesut; Yenidunya, Ali Fazil (TAYLOR & FRANCIS LTD, 2013)Poly(maleic anhydride-co-styrene) (MAST) was synthesized by a free-radical polymerization reaction. A bioactive molecule, procainamide hydrochloride (PH), was then conjugated to MAST. The conjugation product was named as ... -
Synthesis, structural characterization, and antiproliferative/cytotoxic effects of a novel modified poly(maleic anhydride-co-vinyl acetate)/doxorubicin conjugate
Karakus, Gulderen; Ece, Abdulilah; Yaglioglu, Ayse Sahin; Zengin, Haci Bayram; Karahan, Mesut (SPRINGER, 2017)Drug carrier, poly(maleic anhydride-co-vinyl acetate) (MAVA or poly[MA-co-VA]) copolymer, was traditionally synthesized by free radical chain polymerization reaction, in methyl ethyl ketone (MEK) organic media at 80 A ...